That said, there is really only one casino in the region: the Hollywood Casino at Penn National Race Course, located in nearby Grantville, PA. Still, the Pennsylvania home-team fandom is not lacking in this industrial town, so it makes sense that Harrisburg sportsbooks would be a popular draw for the gambling public. As one of the larger cities in the state, Harrisburg sees a fair bit of action itself, though nothing on the level of the major sports areas like Pittsburgh and Philadelphia. Sports betting is a hugely popular activity in the Keystone State, with Pennsylvania residents turning an estimated handle of some $10 billion wagered on athletics each year.